Definition: antibodies attack tissues or cells within the same body while attacking a strange body, because of the similarity of composition
with these cells or tissues, or because they treat the body tissues as strange
Risk of Immune Diseases:
Immune diseases usually attack all the tissues and organs of the body leading to gradual deterioration in the functions of the kidney, heart, liver and nervous system
Patients with immune diseases suffer from:
Anemia (a result of red blood cell fracture)
) Bleeding) due to platelet breakdown & deterioration of liver function (
Deterioration of kidney functions
Heart: The inflammation caused by the immune diseases of the heart muscle to the fibrosis of the heart and membranes, which leads to the deterioration and failure of the heart muscle pumping blood to all organs and tissues of the body, which in turn lead to damage and deterioration of different body organs
The nervous system: from clots and brain hemorrhages, and end to hallucinations, which may reach the final stages of schizophrenia in the personality
Examples of the most common immunological diseases
(SLE)
(RA)
AI thyroiditis " Hashimoto/ Grave's
Type I DM & IDDM )
IBD >> Ulcerative colitis/ crohn’s disease
Sjogren's syndrome
Pernicious anemia "B12 deficiency“
Rheumatic fever
Vitiligo
1ry biliary cirrhosis MS
Myasthenia gravis
Psoriasis
TO diagnose :
ANA >> screening test
Anti ds DNA
Anti Ro/La (SSA/SSB)
APA >> Pernicious anemia "B12 deficiency“
AMA>> 1ry biliary cirrhosis
ASMA>> 1ry biliary cirrhosis
LKM>> 1ry biliary cirrhosis
SLA >> 1ry biliary cirrhosis
ANCA C >> Wegener’s granulomatosis
ASCA >>IBD crohn’s disease
ANCA P >> IBD Ulcerative colitis
Anti TPO/ Anti microsomal Ab >> AI thyroiditis " Hashimoto”